A15 Rapid radiation of treponema pallidum pertenue in wild non-human primates
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چکیده
establish the presence of a more ancient ERV component in the murine genome, comprised of isolated, highly degraded insertions. These sequences evidence a transition in murine evolutionary history, beginning about one million years ago, wherein the ancient ERV families that have counterparts in humans and other large mammals were overtaken by a wave of newly acquired and/or transpositionally active ERVs.
منابع مشابه
Genetic relationship between Treponema pallidum and Treponema pertenue, two noncultivable human pathogens.
Genetic relationships among two strains of Treponema pallidum (Nichols and KKJ) and a strain of T. pertenue were determined by measuring the degree of deoxyribonucleic acid sequence homology. The results in indicated that these three virulent, noncultivable treponemes were genetically indistinguishable. Like T. pallidum (Nichols), T. pertenue (Gauthier) had no detectable deoxyribonucleic acid s...
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BACKGROUND Unclassified simian strain Treponema Fribourg-Blanc was isolated in 1966 from baboons (Papio cynocephalus) in West Africa. This strain was morphologically indistinguishable from T. pallidum ssp. pallidum or ssp. pertenue strains, and it was shown to cause human infections. METHODOLOGY/PRINCIPAL FINDINGS To precisely define genetic differences between Treponema Fribourg-Blanc (uncla...
متن کاملHigh Prevalence of Antibodies against the Bacterium Treponema pallidum in Senegalese Guinea Baboons (Papio papio)
The bacterium Treponema pallidum is known to cause syphilis (ssp. pallidum), yaws (ssp. pertenue), and endemic syphilis (ssp. endemicum) in humans. Nonhuman primates have also been reported to be infected with the bacterium with equally versatile clinical manifestations, from severe skin ulcerations to asymptomatic. At present all simian strains are closely related to human yaws-causing strains...
متن کاملFailure of PCR to Detect Treponema pallidum ssp. pertenue DNA in Blood in Latent Yaws
Yaws, caused by Treponema pallidum ssp. pertenue, is a neglected tropical disease closely related to venereal syphilis and is targeted for eradication by 2020. Latent yaws represents a diagnostic challenge, and current tools cannot adequately distinguish between individuals with true latent infection and individuals who are serofast following successful treatment. PCR on blood has previously be...
متن کاملUltrastructural aspects of infection with Treponema pallidum subspecies pertenue (Pariaman strain).
OBJECTIVE To study ultrastructural aspects of infection with Treponema pertenue (Pariaman strain), originating from West Sumatra, Indonesia. MATERIALS AND METHODS Biopsy material originating from skin lesions in ten young children suffering from early infectious yaws in Indonesia, and rabbit testicular tissue inoculated with T pertenue. Human skin as well as rabbit testicular tissue was exami...
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